Processes of peroxidation of lipids and proteins in organs of rabbits considering the age-old aspect

Abstract

The content of products of lipid peroxidation and products of oxidizing modification of proteins were investigated in the brain, heart and the longest back muscle of New Zealand breed rabbits. During investigations it was set, that concentration of the hydroperoxide of lipids (HPL) during research period was the lowest in the longest back muscle 4,79-5,63 u/g of tissue. The increase of content of TBA-RS was marked in the heart of rabbits with 2,24 mmol/ g of tissue in one-day old animals to 4,85 mmol/g of tissue in 90-day old animals. The oxidizing modification of proteins (OMP) products are the perspective marker of free-radical oxidization level estimation, as this index have the protracted period of disintegration, as compared to products of lipoperoxidation. High content of dynitrophenyhydrazines of basic and neutral character was seen in the brain of one day old rabbits. However, with age, content of ОМP products diminished in the organs of the investigated animals, that testified weakening of free-radical processes and activating of the system of antioxidant defense.