Study of Polymorphism of the MC4R Locus in Pigs of the Large White Breed

Abstract

DNA typing was performed by the PCR-RFLP method at the loci of the MC4R gene The herd of pigs was divided according to origin. Polymorphism of the studied gene is established. The higher frequency of AA and AG genotypes was in animals of French breeding, and the homozygous GG genotype was in crossbred animals. Accordingly, allele A had a higher frequency in French breeding animals and allele B – in crossbred animals. According to the studied gene, genetic balance is absent only in crossbred animals. A high coefficient of genetic similarity was established between French and Belgian breeding animals. Most of the existing breeders have a heterozygous genotype.